General: H Vanderstichele, G De Meyer, F Shapiro, S Engelborghs, PP De Deyn, L M Shaw, JQ Trojanowski. ALZHEIMER’S DISEASE BIOMARKERS: FROM CONCEPT TO CLINICAL UTILITY (Chapter 5). In: BioMarkers for Early Diagnosis of Alzheimer’s Disease ISBN: 978-1-60456-991-9. Editors: D. Galimberti, E. Scarpini, pp. 81-122 © 2008 Nova Science Publishers, Inc..
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• PRE – ANALYTICAL phase
• ANALYTICAL phase
  • Biomarker selection
  • Improvements of test protocols
  • Assay qualification
  • Assay validation
• POST – ANALYTICAL phase
• • Quality control program
  • Biomarker signatures
  • Assay (technology) comparison
  • Assay integration in world-wide consortia